Indwara ya kanseri yibara yiyongera kubarwayi ba kanseri ya prostate kubuvuzi bwa androgene
Indwara ya kanseri yibara yiyongera kubarwayi ba kanseri ya prostate kubuvuzi bwa androgene
Anonim

Nk’uko ubushakashatsi bwashyizwe ahagaragara ku ya 10 Ugushyingo mu kinyamakuru cy’ikigo cy’igihugu gishinzwe kanseri kibitangaza, abagabo bafata imiti yo kubura androgène (ADT) kuri kanseri ya prostate barashobora kugira ibyago byinshi byo kurwara kanseri yu mura.

Ubuvuzi bwa Androgène ni ubuvuzi bwateganijwe cyane ku bagabo barwaye kanseri ya prostate, nubwo ikoreshwa ry’indwara ziterwa n'indwara nkeya bikomeje kutavugwaho rumwe, bitewe n'ingaruka mbi zirimo osteoporose, indwara z'umutima n'imitsi, diyabete n'umubyibuho ukabije; bibiri bya nyuma ni ibintu bishobora gutera kanseri yibara.

Kugira ngo hamenyekane niba abarwayi ba kanseri ya prostate bafata imiti yo kubura androgène bafite ibyago byinshi byo kurwara kanseri y'amara, Silke Gillessen, MD, wo mu bitaro bya Cantonal i St. Gallen, mu Busuwisi na bagenzi be, bakoze ubushakashatsi bwakozwe ku bagabo barwaye kanseri ya prostate bamenyekanye binyuze kuri Ubushakashatsi, Epidemiologiya, nibisubizo byanyuma (SEER) ububiko bwikigo cyigihugu cya kanseri. By'umwihariko, bagaragaje abagabo 107, 859 bafite imyaka 67 cyangwa irenga basuzumwe kanseri ya prostate hagati ya 1993 na 2002, bakurikiranwa kugeza 2004. Abagabo bakiriye ADT haba muburyo bwa hormone irekura gonadotropine (GnRH), cyangwa orchiectomy.

Abashakashatsi basanze nyuma yo guhindura ibintu bitesha umutwe nk'imyaka n'imibereho n'imibereho myiza y'abaturage, habayeho kwiyongera 30-40% ugereranije na kanseri yibara mu bagabo bavuwe na ADT ugereranije nabatayifite. Byongeye kandi, igihe kirekire abagabo bafashe ADT, niko ibyago byabo byo kurwara kanseri yibara. Nyamara, ubushakashatsi buracyakenewe kugirango hamenyekane ingaruka zo kuvurwa mugihe kirekire kuruta uko byagaragaye muri ubu bushakashatsi.

Abanditsi banditse ko ibisubizo by’ubushakashatsi bishobora kugira "ingaruka zikomeye" ku bagabo barwaye kanseri ya prostate bafata ADT, cyane cyane ababana n’indwara yaho, ikura buhoro, kuri bo igihe ADT ikaba ari kirekire.

Mu nyandiko iherekeje, Jennifer H. Lin, impamyabumenyi y'ikirenga, na Edward Giovannucci, MD, wo mu bitaro bya Brigham n'abagore i Boston banditse ko ubushakashatsi bwerekana ko ibyago byinshi byo kurwara kanseri y'amara bishobora kuba ikindi cyifuzo mu cyemezo cyo gukoresha ADT, cyane cyane ukurikije ingaruka n'ingaruka zabyo mubuzima bwiza.

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